Product Name :
SARA Recombinant Rabbit Monoclonal Antibody [JE63-65]
Predicted band size :
156 kDa
Observed band size :
156 kDa
Synonyms:
CG15667 antibody hSARA antibody LD33044p antibody Madh-interacting protein antibody MADHIP antibody Mothers against decapentaplegic homolog-interacting protein antibody Novel serine protease antibody NSP antibody Receptor activation anchor antibody SAR1 antibody 展开
Function :
Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization. This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within human SARA aa 1-50/1,425.
Species reactivity:
Human, Rat
Verify application:
WB
Coupling :
unconjugated
Clone number:
JE63-65
RRID:
AB_3072147
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.Price of 1350518-27-2 Aliquot store at -20℃.Price of 1554086-90-6 Avoid repeated freeze / thaw cycles.PMID:33495654
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 156 kDa
Positive control :
HUVEC cell lysate, rat brain tissue lysate, Hela cell lysate, SiHa cell lysate, PC-3 cell lysate.