3-Acetylpyridine adenine dinucleotide (CAS 86-08-8)
Product Name :
3-Acetylpyridine adenine dinucleotide (CAS 86-08-8)
Synonym :
APAD, Oxidized
Application :
3-Acetylpyridine adenine dinucleotide is an analog of NAD
CAS:
86-08-8
Purity:
≥92%
Molecular Weight:
662.44
Formula :
C22H28N6O14P2
Physical state:
Solid
solubility :
Soluble in water
Shipping Condition :
Store at -20° C
Melting point:
SMILES:
CC(=O)C1=C[N+](=CC=C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C4N=CN=C5N)O)O)O)O
References:
:The kinetic properties and sensitivities to inhibitors of lactate dehydrogenases (LDH1 and LDH2) from Toxoplasma gondii: comparisons with pLDH from Plasmodium falciparum.157327-48-5 Description | Dando, C., et al. 2001. Mol Biochem Parasitol. 118: 23-32. PMID: 11704270Kinetics of the transhydrogenase reaction catalyzed by mitochondrial NADH:ubiquinone oxidoreductase (complex I). | Zakharova, NV. 2002. Biochemistry (Mosc). 67: 651-61. PMID: 12126472Structure of Toxoplasma gondii LDH1: active-site differences from human lactate dehydrogenases and the structural basis for efficient APAD+ use. | Kavanagh, KL., et al. 2004. Biochemistry. 43: 879-89. PMID: 14744130Molecular cloning and characterization of a novel lactate dehydrogenase gene from Clonorchis sinensis. | Yang, G., et al. 2006. Parasitol Res. 99: 55-64. PMID: 16479375Artificial electron carriers for photoenzymatic synthesis under visible light. | Lee, SH., et al. 2012. Chemistry. 18: 5490-5. PMID: 22488767An enzymatic cycling method for 3-acetylpyridine adenine dinucleotide to increase the sensitivity of enzymatic methods which employ this NAD analog. | Ferrier, B. 1990. Anal Biochem. 186: 229-32. PMID: 2363493Thioredoxin Reductase-Type Ferredoxin: NADP+ Oxidoreductase of Rhodopseudomonas palustris: Potentiometric Characteristics and Reactions with Nonphysiological Oxidants. | Lesanavičius, M., et al. 2022. Antioxidants (Basel). 11: PMID: 35624864Analysis of the kinetic mechanism of enterococcal NADH peroxidase reveals catalytic roles for NADH complexes with both oxidized and two-electron-reduced enzyme forms. | Crane, EJ., et al. 1995. Biochemistry. 34: 14114-24. PMID: 7578008The mechanism of hydride transfer between NADH and 3-acetylpyridine adenine dinucleotide by the pyridine nucleotide transhydrogenase of Escherichia coli.12354-84-6 custom synthesis | Glavas, NA.PMID:33547999 and Bragg, PD. 1995. Biochim Biophys Acta. 1231: 297-303. PMID: 7578217High cyclic transhydrogenase activity catalyzed by expressed and reconstituted nucleotide-binding domains of Rhodospirillum rubrum transhydrogenase. | Yamaguchi, M. and Hatefi, Y. 1997. Biochim Biophys Acta. 1318: 225-34. PMID: 9030266Protein engineering tests of a homology model of Plasmodium falciparum lactate dehydrogenase. | Hewitt, CO., et al. 1997. Protein Eng. 10: 39-44. PMID: 9051732Catalytic properties of lipoamide dehydrogenase from Mycobacterium smegmatis. | Marcinkeviciene, J. and Blanchard, JS. 1997. Arch Biochem Biophys. 340: 168-76. PMID: 9143318The reduction of acetylpyridine adenine dinucleotide by NADH: is it a significant reaction of proton-translocating transhydrogenase, or an artefact? | Stilwell, SN., et al. 1997. Biochim Biophys Acta. 1320: 83-94. PMID: 9186780Mutations at tyrosine-235 in the mobile loop region of domain I protein of transhydrogenase from Rhodospirillum rubrum strongly inhibit hydride transfer. | Bizouarn, T., et al. 1997. Biochim Biophys Acta. 1320: 265-74. PMID: 9230921Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum. | Gomez, MS., et al. 1997. Mol Biochem Parasitol. 90: 235-46. PMID: 9497046
Product Name :
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid (CAS 34576-94-8)
Synonym :
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid is also known as 3,6-dichloro-1-benzothiophene-2-carboxylate.
Application :
3,6-Dichloro-benzo[b]thiophene-2-carboxylic acid is an inhibitor of myeloid cell leukemia 1 (Mcl-1) and useful biochemical for proteomics research.
CAS:
34576-94-8
Purity:
≥95%
Molecular Weight:
247.10
Formula :
C9H4Cl2O2S
Physical state:
Solid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
284-290° C
SMILES:
C1=CC2=C(C=C1Cl)SC(=C2Cl)C(=O)O
References:
:3,6-dichlorobenzo[b]thiophene-2-carboxylic acid alleviates ulcerative colitis by suppressing mammalian target of rapamycin complex 1 activation and regulating intestinal microbiota.172324-67-3 web | He, QZ.1583-58-0 Safety Information , et al.PMID:33497273 2022. World J Gastroenterol. 28: 6522-6536. PMID: 36569276
Product Name :
3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester (CAS 862129-81-5)
Synonym :
Application :
CAS: 862129-81-5, MF: C11H19BO2S, MW: 226.14
CAS:
862129-81-5
Purity:
Molecular Weight:
226.36805-97-7 SMILES 14
Formula :
C11H19BO2S
Physical state:
solubility :
Shipping Condition :
Melting point:
SMILES:
B1(OC(C(O1)(C)C)(C)C)C2=CCSCC2
References:
1439823-01-4 chemscene PMID:33605198
Product Name :
3-(5-Fluoro-2,4-dinitroanilino)-2,2,5,5,-tetramethyl-1-pyrrolidinyloxy (CAS 73784-45-9)
Synonym :
3-[(5-Fluoro-2,4-dinitrophenyl)amino]-2,2,5,5-tetramethyl-1-pyrrolidinyloxy
Application :
3-(5-Fluoro-2,4-dinitroanilino)-2,2,5,5,-tetramethyl-1-pyrrolidinyloxy is a stable free radical and spin label compound
CAS:
73784-45-9
Purity:
Molecular Weight:
341.31
Formula :
C14H18FN4O5
Physical state:
Solid
solubility :
Shipping Condition :
Store at -20° C
Melting point:
SMILES:
CC1(C)CC(NC2=C(C=C(C(F)=C2)[N+]([O-])=O)[N+]([O-])=O)C(C)(C)N1O
References:
236406-49-8 SMILES 85073-19-4 chemscene PMID:33459098
Product Name :
3,5-Dinitrobenzamide (CAS 121-81-3)
Synonym :
Nitromide
Application :
CAS:
121-81-3
Purity:
Molecular Weight:
211.13
Formula :
C7H5N3O5
Physical state:
Solid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
SMILES:
NC(=O)C1=CC(=CC(=C1)[N+]([O-])=O)[N+]([O-])=O
References:
:Identification of the major urinary and fecal metabolites of 3,5-dinitrobenzamide in chickens and rats. | Shappell, NW., et al. 1999. Chemosphere. 38: 1757-62. PMID: 10101847Discrimination of enantiomers of alpha-amino acids by chiral derivatizing reagents from trans-1,2-diaminocyclohexane. | Kaik, M., et al. 2008. Chirality. 20: 301-6. PMID: 17600850Mechanism of action and preclinical antitumor activity of the novel hypoxia-activated DNA cross-linking agent PR-104. | Patterson, AV., et al. 2007. Clin Cancer Res. 13: 3922-32. PMID: 17606726The nitroreductase prodrug SN 28343 enhances the potency of systemically administered armed oncolytic adenovirus ONYX-411(NTR). | Singleton, DC., et al. 2007. Cancer Gene Ther. 14: 953-67. PMID: 17975564Metabolism and excretion of the novel bioreductive prodrug PR-104 in mice, rats, dogs, and humans. | Gu, Y., et al. 2010.13815-94-6 supplier Drug Metab Dispos.56553-60-7 Synonym 38: 498-508. PMID: 20019245Decomposition of 3,5-dinitrobenzamide in aqueous solution during UV/H2O2 and UV/TiO2 oxidation processes.PMID:33753561 | Yan, Y., et al. 2017. Environ Sci Pollut Res Int. 24: 5360-5369. PMID: 28013465Design, synthesis and antimycobacterial activity of 3,5-dinitrobenzamide derivatives containing fused ring moieties. | Wang, A., et al. 2018. Bioorg Med Chem Lett. 28: 2945-2948. PMID: 30006066Practical screening procedure for chloramphenicol in milk at low parts per billion level. | Schwartz, DP. and McDonough, FE. 1984. J Assoc Off Anal Chem. 67: 563-5. PMID: 6746480The metabolic fate of nitromide in the rat. I. Metabolism and excretion. | Facchini, V. and Griffiths, LA. 1980. Xenobiotica. 10: 289-97. PMID: 7415210
Product Name :
3,5-Dimethoxybenzylzinc chloride solution (CAS 352530-33-7)
Synonym :
Application :
CAS: 352530-33-7, MF: C9H11ClO2Zn, MW: 252.03
CAS:
352530-33-7
Purity:
Molecular Weight:
252.03
Formula :
C9H11ClO2Zn
Physical state:
solubility :
Shipping Condition :
Store at 4° C
Melting point:
SMILES:
COC1=CC(=CC(=C1)[CH2-])OC.158923-11-6 custom synthesis [Cl-].5337-93-9 manufacturer [Zn+2]
References:
Product Name :
3,5-dichloro-4-(difluoromethoxy)aniline
Synonym :
Application :
CAS:
Purity:
Molecular Weight:
228.6945-92-2 supplier 02
Formula :
C7H5Cl2F2NO
Physical state:
Solid
solubility :
Shipping Condition :
Store at room temperature
Melting point:
SMILES:
C1=C(C=C(C(=C1Cl)OC(F)F)Cl)N
References:
1470372-59-8 manufacturer PMID:33558295
Product Name :
3,5-dibromo-2-chlorobenzoic acid
Synonym :
Application :
MW: 314.36
CAS:
Purity:
Molecular Weight:
Formula :
Physical state:
solubility :
Shipping Condition :
Melting point:
126.3006-60-8 Formula 03° C (Predicted)
SMILES:
C1=C(C=C(C(=C1Br)Cl)C(=O)O)Br
References:
49845-33-2 Molecular Weight PMID:33438819
Product Name :
3-(5-Chloro-2-methoxy-phenyl)-2-mercapto-7-methyl-5,6,7,8-tetrahydro-3H-benzo[4,5]thieno[2,3-d]pyrimidin-4-one
Synonym :
Application :
CAS:
Purity:
Molecular Weight:
392.92
Formula :
C18H17ClN2O2S2
Physical state:
solubility :
Shipping Condition :
Store at room temperature
Melting point:
SMILES:
CC1CCC2=C(C1)SC3=C2C(=O)N(C(=S)N3)C4=C(C=CC(=C4)Cl)OC
References:
15932-93-1 chemscene 771-61-9 SMILES PMID:33683157
Product Name :
3,5-Bis-(thiophene-2-sulfonylamino)-benzoic acid
Synonym :
Application :
CAS:
Purity:
Molecular Weight:
444.53
Formula :
C15H12N2O6S4
Physical state:
solubility :
Shipping Condition :
Store at room temperature
Melting point:
SMILES:
C1=CSC(=C1)S(=O)(=O)NC2=CC(=CC(=C2)C(=O)O)NS(=O)(=O)C3=CC=CS3
References: