Product Name :
TLR9 Recombinant Rabbit Monoclonal Antibody [JE59-91]
Predicted band size :
116 kDa
Observed band size :
116 kDa
Synonyms:
CD 289 antibody CD289 antibody TLR 9 antibody TLR9 antibody TLR9_HUMAN antibody Toll like receptor 9 antibody Toll like receptor 9 isoform A precursor antibody Toll like receptor 9 isoform B antibody Toll-like receptor 9 antibody
Function :
Toll-like receptor 9 is a protein that in humans is encoded by the TLR9 gene. TLR9 has also been designated as CD289 (cluster of differentiation 289). It is a member of the toll-like receptor (TLR) family. TLR9 is an important receptor expressed in immune system cells including dendritic cells, macrophages, natural killer cells, and other antigen presenting cells.191348-16-0 Formula TLR9 is expressed on endosomes internalized from the plasma membrane, binds DNA (preferentially DNA containing unmethylated CpGs of bacterial or viral origin), and triggers signaling cascades that lead to a pro-inflammatory cytokine response.3,6-Dichloro-5-methyl-1,2,4-triazine web Cancer, infection, and tissue damage can all modulate TLR9 expression and activation.PMID:33662625 TLR9 is also an important factor in autoimmune diseases, and there is active research into synthetic TLR9 agonists and antagonists that help regulate autoimmune inflammation.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Recombinant protein within Human TLR9 aa 361-560 / 1,032.
Species reactivity:
Human
Verify application:
WB
Coupling :
unconjugated
Clone number:
JE59-91
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 116 kDa
Positive control :
Daudi cell lysate, Raji cell lysate, RPMI 8226 cell lysate.