Product Name :
PAK5 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
EC 2.7.11.1 antibody KIAA1264 antibody MGC26232 antibody p21 activated kinase 7 antibody p21 protein (Cdc42/Rac)-activated kinase 7 antibody p21(CDKN1A) activated kinase 7 antibody p21-activated kinase 5 antibody p21-activated kinase 7 antibody PAK 5 antibody PAK 7 antibody 展开
Function :
The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
The antiserum was produced against synthesized peptide derived from human PAK7. AA range:661-710
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IHC-P
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing.2-Amino-2-methyl-1-propanol manufacturer Aliquot store at -20℃ or -80℃.1H-Indole-6-carbaldehyde uses Avoid repeated freeze / thaw cycles.PMID:33446085
Storage buffer solution:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Subtype:
IgG
Purification method :
Immunogen affinity purified.
ELTSA :
Molecular weight :
80 kDa
Positive control :
Brain,Tongue,