Product Name :
PU.1/Spi1 Recombinant Rabbit Monoclonal Antibody [JB72-35]
Predicted band size :
Observed band size :
Synonyms:
transcription factor spi1 antibody 31 kDa Transforming Protein antibody 31 kDa-transforming protein antibody cb1086 antibody Hematopoietic transcription factor PU.1 antibody OF antibody oncogene spi1 antibody PU.1 antibody SFFV virus-induced murine erythroleukemia oncogene, mouse, homolog of antibody SFPI1 antibody 展开
Function :
Transcription factor PU.1 is a protein that in humans is encoded by the SPI1 gene. This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development.NH2-PEG8-OH site The nuclear protein binds to a purine-rich sequence known as the PU-box found on enhancers of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes.4-Bromobenzoic acid Order Multiple transcript variants encoding different isoforms have been found for this gene. The ETS domain is the DNA-binding module of PU.1 and other ETS-family transcription factors.
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human PU1 / Spi1 aa 1-50 / 270.PMID:33686748
Species reactivity:
Human
Verify application:
WB, IHC-P, FC
Coupling :
unconjugated
Clone number:
JB72-35
RRID:
AB_3070759
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 31 kDa
Positive control :
THP-1 cell lysates, human spleen tissue, human tonsil tissue, K562.